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Glucosamine 1000mg and 1500mg.

Glucosamine sulphate is a substance that is naturally made in the body. It is needed in the body to produce molecules for laying down new framework tissues in damaged joints. Glucosamine is essential for the production of new cartilage and synthesis of the joints' oil (synovial fluid). Larger quantaties of Glucosamine are needed when damaged joints are healing and, as production of Glucosamine is normally a slow process, it is often in short supply.

Healthy cartilage requires four things. These are:

1. Water for lubrication and nourishment.
2. Proteoglycans to attract and hold water.
3. Collagen to hold proteoglycans in place.
4. Chondrocytes to clean away old proteoglycans and collagen plus produce new ones.

When any one of these elements is missing, cartilage can deteriorate and osteoarthritis will begin to develop. However, with effective treatment, much of this can be prevented and also rehabilitated if you are currently suffering from osteoarthritis.

One of the most effective supplements for osteoarthritis is a compound called glucosamine. Glucosamine is an amino sugar produced from the shells of chitin (shellfish) and is a key component of cartilage. Glucosamine works to stimulate joint function and repair. It has been proven effective in numerous scientific trials for easing osteoarthritis pain, aiding in the rehabilitation of cartilage, renewing synovial fluid, and repairing joints that have been damaged from osteoarthritis.

Each person produces a certain amount of glucosamine within their bodies. When people grow older, their bodies lose the capacity to make enough glucosamine. Having ample glucosamine in your body is essential to producing the nutrients needed to stimulate the production of synovial fluid, the fluid that lubricates your cartilage and keeps your joints healthy. Without enough glucosamine, the cartilage in their weight-bearing joints, such as the hips, knees, and hands deteriorates. The cartilage then hardens and forms bone spurs, deformed joints, and limited joint movement. This is how the debilitating disease of osteoarthritis develops.

Glucosamine has been shown to reduce pain for osteoarthritis sufferers and improves the joint structure.

The suggested dose for Glucosamine supplementation is 1000 - 2000mg per day.

Contra-indications/Precautions

People who need to be extra careful while supplementing their diet with Glucosamine Sulfate include:

Children and pregnant women, as there have been no studies done to determine its effects on a child or on a developing fetus.

Although there was initial concerns about glucosamine affecting glucose levels in the body (likely due to confusion over the name glucosamine being similar to glucose), there is little evidence that glucosamine actually raises blood sugar, whether diabetic or not. Glucosamine does not raise blood sugar by providing an additional source of glucose. However, many factors can affect insulin secretion and blood glucose levels in diabetic patients, and we recommend that individuals with Diabetes check their blood glucose levels frequently when initiating Glucosamine into their regimen.

If you are allergic to shellfish, consult your doctor before deciding to take Glucosamine. In most cases, however, allergies are caused by proteins in shellfish, not chitin, a carbohydrate from which Glucosamine is extracted.
High dosages of Glucosamine (over 10,000 mg a day) may cause gastric problems, nausea, diarrhea, indigestion, and heartburn. Glucosamine should be taken with meals to help avoid these problems. [top]

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