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This is not a medical site. Information on
this page is provided on a "best efforts" basis for interest
only and does not constitute personal advice.
It is essential that you discuss medical matters with your doctor.
Maitake - Potent
Mushroom
In Japan, Maitake Mushroom is called "King
of Mushroom". Maitake is a very large mushroom (the size of
a basketball), which grows deep in the mountains of North-eastern
Japan. Maitake is extremely sensitive to environmental changes,
which has presented many challenges to those cultivating this mushroom.
Only recently have Japanese farmers succeeded in producing high-quality
organic Maitake Mushrooms, allowing for wider availability.
The fruiting body and the mycelium of Maitake
are used medicinally. In China and Japan, Maitake Mushrooms have
been consumed for 3000 years.
In the late 1980s, Japanese scientists identified
the Maitake to be more potent than lentinan, shiitake, suehirotake,
and kawaratake mushrooms, all used in traditional Asian medicine
for immune function enhancement. Historically, Maitake has been
used as a tonic and adaptogen. It was used as a food to help promote
wellness and vitality. Traditionally, consumption of the mushroom
was thought to prevent high blood pressure and cancer - two applications
that have been the focal point of modern research. The polysaccharides
present in Maitake have a unique structure, and are among the most
powerful to be studied to date. The primary polysaccharide, beta-D-glucan,
is well absorbed when taken orally and is currently under review
for the prevention & treatment of cancer, and as a supportive
tool for HIV infection. Clinical research with Maitake Mushroom
has increased dramatically in the past several years. Laboratory
studies have shown that Maitake Mushroom extract can inhibit the
growth of tumors and stimulate the immune system of cancerous mice.
Human clinical studies of patients with breast and colorectal cancers
are currently under way in the United States. In China, 63 patients
with lung, stomach, or liver cancers or leukemia who took four capsules
of Maitake extract three times daily before meals for one to three
months showed an "anticancer" effect. Reports that Maitake
may help AIDS patients fight Kaposi's sarcoma and other symptoms
are preliminary and require further scientific studies.
Additionally, people with non-insulin-dependent
diabetes mellitus (NIDDM) may also benefit from Maitake, according
to researchers Hiroaki Nanba and Keiko Kubo, authors of "Mushroom
Biology and Mushroom Products". Researchers investigated a
specific, high-molecular polysaccharide in Maitake called the X-fraction.
They found that mice given Maitake had an increased ability to recognize
glucose, and the control group had higher blood glucose levels.
The researchers suggested that Maitake can reduce insulin resistance,
thereby increasing insulin sensitivity. The X-fraction appears to
be the active compound with anti-diabetic properties.
Maitake Mushroom (Grifola frondosa) may best
be known for its cancer-fighting properties. It contains grifolan,
an important beta-glucan polysaccharide (molecule composed of many
sugar molecules linked together). Grifolan has been shown to activate
macrophages, a type of cell consider the " heavy artillery":
of the immune system, explains Larry A. Walker, Ph.D., R.D., author
of "Natural products update," published in Drug Topics,
June 1997. D-fraction, one of the polysaccharides in maitake mushroom,
also energized the cellular immune system.
The evidence confirming maitake's therapeutic
value - both in and out of the laboratory - is impressive. Laboratory
studies have shown that maitake extract can block the growth of
cancer tumors and boost the immune function of mice with cancer.
Haroaki Nanba reported the findings of the following
study in "Maitake D-fraction: healing and preventing potentials
for cancer," published in the Townsend Letter for Doctors and
Patients, Feb/Mar 1996; In a non-randomized clinical study, 165
individuals with advanced cancer used maitake D-fraction. Patients
received either maitake D-fraction alone or with chemotherapy. Maitake
mushroom was found effective against leukemia and stomach and bone
cancers. Responses were further improved when maitake D-fraction
and chemotherapy were used together. Individuals receiving maitake
D-fraction also experienced relief from the side effects of chemotherapy,
such as loss of appetite, vomiting, nausea, hair loss, and deficiency
of white blood cells.
People with Type 2 Diabetes may also benefit
from maitake mushroom, according to researchers Hiroaki Nanba and
Keiko Kubo, authors of "Mushroom biology and mushroom products".
Researchers investigated a specific, high-molecular polysaccharide
in maitake called the X-fraction. They found that mice given maitake
had an increased ability to recognize glucose, and the control group
had higher blood glucose levels. The researchers suggested that
maitake mushroom can reduce insulin resistance, thereby increasing
insulin sensitivity. The X-fraction appears to be the active compound
with anti-diabetic properties.
In addition, many doctors in Japan use maitake
mushroom to lower blood pressure and blood lipids, two key risk
factors in cardiovascular disease.
Beinfield also recommends maitake mushroom for
stomach ailments. "It aids digestion by regulating the stomach
and intestines, and helps eliminate food stagnation," she explains.
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